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蛋白酶激活受体2激活的结构基础和偏向的激进作用

Xinyan Zhu1, Ruixue Xia1, Anqi Zhang1

  • 1HIT Center for Life Sciences, School of Life Science and Technology, Faculty of Life Sciences and Medicine, Harbin Institute of Technology, Harbin, Heilongjiang, China.

Cell discovery
|December 2, 2025
PubMed
概括

蛋白酶激活受体2 (PAR2) 激活由其连接联体 (TL) 进行结构性阐明,使用冷EM. 这揭示了PAR2是如何参与G蛋白的,并使偏向连接体的设计能够用于治疗应用.

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