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Updated: Jan 9, 2026

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纤维细胞表观基因组是突肉瘤中SS18::SSX介导的转变的基础

Lesley A Hill1,2, R Wilder Scott1,2, Lauren A Martin1,2

  • 1Biomedical Research Centre, Vancouver, BC, Canada.

Nature communications
|December 2, 2025
PubMed
概括

研究人员确定了突肉瘤 (SyS) 罕见的中细胞 stromal 细胞 (MSC) 起源. SS18::SSX融合瘤基因通过揭露胚胎MSC程序来驱动SyS,从而导致瘤的发展.

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