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反菌体防御系统Retron-Eco7的结构机制

Junichiro Ishikawa1, Kanta Yoneyama1, Aa Haeruman Azam2

  • 1Department of Chemistry and Biotechnology, Graduate School of Engineering, The University of Tokyo, Tokyo, Japan.

Nature communications
|December 2, 2025
PubMed
概括

作为一种细菌抗菌体系统的Retron-Eco7,它使用逆转录酶-DNA复合体来抑制效应蛋白. 核酶触发了这个系统,导致宿主tRNA分裂和流产性感染.

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