通过抑制控制,注意力和工作记忆的神经分离通过抑制控制
Yueyao Liu1, Yingtao Fu1, Enze Tang1
1Department of Psychology and Behavioral Sciences, Zhejiang University, Hangzhou, China.
Nature communications
|December 2, 2025
概括
注意力和工作记忆 (WM) 是可以分离的,而不是一个连续的过程. 超边缘环 (SMG) 使用抑制控制来调节WM的信息选择,挑战传统观点.
科学领域:
- 认知神经科学 认知神经科学
- 神经成像是一种神经成像.
- 人类大脑研究 人类大脑研究
背景情况:
- 注意力和工作记忆 (WM) 传统上被视为相互关联的认知功能.
- 注意力通常被描述为WM的守门员,控制信息编码和存储.
- 现有研究表明,注意力和WM的共同神经支.
研究的目的:
- 为了研究注意力和WM编码之间的神经分离.
- 为了确定特定的大脑区域和机制,这种解离的基础.
- 为了因果测试确定区域在规范WM信息选择中的作用.
主要方法:
- 多模式方法结合了功能性MRI (fMRI),动态因果建模 (DCM),跨直流刺激 (tDCS) 和跨磁刺激 (TMS).
- 使用专门设计用于区分注意力过程和WM编码的任务.
- 采用神经调节技术 (tDCS和TMS) 来确定因果关系.
主要成果:
- 功能性核磁共振扫描 (MRI) 确定了上边脊椎 (SMG) 作为分离注意力和WM的关键区域.
- 动态因果建模显示,SMG对WM集成的注意力表征施加抑制控制.
- 神经调节 (tDCS和TMS) 证实,增强SMG活动因果强化了这种抑制控制,具有可泛化的效应.
结论:
- 注意和WM编码是不同的神经过程,挑战了连续关系的观点.
- 超边缘环在通过抑制控制调节信息选择方面发挥着关键的因果作用.
- 这些发现为支持认知控制和记忆形成的神经架构提供了更细致的理解.
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