诺莫图预测结肠癌的短期和长期结果,基于CT身体组成
Zechen Lu1, Wenchang Yang1, Hanyu Yang1
1Department of Gastrointestinal Surgery, Affiliated Hospital of Qingdao University, Qingdao, 266400, Shandong Province, China.
International journal of colorectal disease
|December 2, 2025
概括
在结肠癌患者中,肉类预测术后并发症和无复发生存期 (RFS). 骨髓炎也独立地预测RFS,帮助临床决策和改善结果.
科学领域:
- 在瘤学瘤学.
- 老年病的医生 老年病的医生
- 放射学 放射学是一门学科.
背景情况:
- 调查萨尔科佩尼亚 (低骨肌指数,SMI) 和骨髓炎 (高肌肉间脂肪组织,IMAT) 对接受手术的结肠癌 (CC) 患者的影响.
- 检查身体组成,手术后不良事件和无复发生存率 (RFS) 之间的关联.
研究的目的:
- 确定肉症和骨髓炎是否是手术后并发症和CC患者的RFS的独立预测因素.
- 根据身体组成和临床因素,开发和验证用于预测CC患者的RFS的诺姆图.
主要方法:
- 追溯分析475名患者 (原始队列) 和209名患者 (验证队列) 的CC进行了彻底切除.
- 使用考克斯的比例危险和后勤回归模型来评估身体组成和结果之间的相关性.
- 开发和评估一个用于RFS预测的nomogram.
主要成果:
- 麻症 (低SMI) 和低albuminemia是术后并发症的独立危险因素.
- 低IMAT和高SMI是RFS的独立预后变量.
- 开发的名图表在两个队列中都显示了强大的RFS预测性能.
结论:
- 石症是CC患者术后并发症和RFS的重要预测因素.
- 骨髓炎独立预测RFS,突出其临床相关性.
- 诺米图提供了有价值的临床决策支持,以改善CC患者的治疗结果.
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