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Updated: Jan 9, 2026

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空间奥米克:在瘤微环境的分析中的应用和实用性

Ji-Eun See1, Sarah Barlow2,1, Wani Arjumand2,1

  • 1Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN, USA.

Cancer metastasis reviews
|December 2, 2025
PubMed
概括

空间奥米克技术在组织中绘制基因表达图,彻底改变了生物医学研究. 这些空间转录学工具通过详细介绍瘤微环境和指导精确瘤学来增强癌症研究.

关键词:
癌症研究 癌症研究精准医学是一门精准的医学.空间转录组学 空间转录组学瘤异质性 瘤异质性瘤微环境是一个微环境.瘤-免疫相互作用

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Every normal cell or tissue is embedded in a complex local environment called stroma, consisting of different cell types, a basal membrane, and blood vessels. As normal cells mutate and develop into cancer cells, their local environment also changes to allow cancer progression. The tumor microenvironment (TME) consists of a complex cellular matrix of stromal cells and the developing tumor. The cross-talk between cancer cells and surrounding stromal cells is critical to disrupt normal tissue...
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