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Updated: Jan 9, 2026

Chemical Inactivation of the E3 Ubiquitin Ligase Cereblon by Pomalidomide-based Homo-PROTACs
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CCA-1.1 破坏MYC蛋白质的稳定,在肝细胞癌中诱导不可逆转的抗增殖作用

Rohmad Yudi Utomo1,2, Novia Permata Hapsari3, Nadzifa Nugraheni3

  • 1Cancer Chemoprevention Research Center, Faculty of Pharmacy, Universitas Gadjah Mada, Sleman, Yogyakarta, Indonesia. rohmad.yudi.utomo@ugm.ac.id.

Medical oncology (Northwood, London, England)
|December 2, 2025
PubMed
概括

CCA-1.1通过向MYC蛋白质,抑制增殖,并诱导细胞死亡途径,如细胞亡和衰老,有效地对抗肝细胞癌 (HCC).

关键词:
自自是一种自的过程.这就是C-Mycc.CCA-1.1.1 这是一本书.库尔库明是一种黄素.这就是N-Myc.

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