乳头湿疹的现实流行情况和相关因素在患有无氧性皮肤炎的患者
Jung Min Lee1, Yu Jin Lee1, Yun Jeong Choi1
1Department of Dermatology, Nowon Eulji Medical Center, Eulji University School of Medicine, Seoul, Korea.
Annals of dermatology
|December 2, 2025
概括
乳头湿疹 (NE) 影响27.5%的亚托皮性皮肤炎 (AD) 患者,主要是女性. 这种情况显著影响生活质量,并与更严重的AD症状有关.
科学领域:
- 皮肤病学 皮肤病学
- 临床研究 临床研究
- 流行病学 流行病学
背景情况:
- 乳头湿疹 (NE) 是一种和疼痛的皮肤疾病,影响乳头.
- 它在6%-23%的阿托皮性皮肤炎 (AD) 患者中被观察到,青少年和年轻成人女性的患病率更高.
研究的目的:
- 为了确定在被诊断为AD的患者中NE的患病率.
- 在AD患者中确定与NE相关的临床因素.
主要方法:
- 从7月到2023年12月进行了一项回顾性横截面研究.
- 招募了200名患有AD的患者,并填写了一份关于AD和NE症状及其对日常生活的影响的问卷.
主要成果:
- 在AD患者中NE的患病率为27.5% (200人中55人).
- NE在女性中明显更常见 (70.9%vs38.6%),与女性性别相关,增加了AD和疼痛得分,以及更高的Investigator全球评估得分.
- 很大一部分患者 (35.8%) 报告说,由于NE,与健康相关的生活质量 (HRQoL) 严重受损,其中45.3%经历了严重的情绪困扰.
结论:
- 乳头湿疹,尽管影响一个小的身体区域,与更严重的亚托邦性皮肤炎有关.
- 皮肤科医生应该认识到NE对患者HRQoL和情绪健康的重大影响.
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