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Updated: Jan 9, 2026

Mouse Naïve CD4+ T Cell Isolation and In vitro Differentiation into T Cell Subsets
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一个依赖于微生物群和IL-15的与生俱来的类似B细胞原始体,表达E4BP4BP4

Junming He1,2, Xinlei Hou3, Xiaomei Feng4,5,6,7

  • 1Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, 102218, China.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
|December 2, 2025
PubMed
概括

研究人员确定了一种新的与生俱来的类似B细胞原始体,称为NK-B细胞,在PDK1缺乏的小鼠中得到丰富. 这些细胞由IL-15和肠道微生物群调节,表达E4BP4并分化为B细胞.

关键词:
B细胞是B细胞的组成部分.它们包括IL-15和E4BP4.在 NK 细胞中, NK 细胞是最重要的.在NK-B中,它是NK-B.在PDK1中,PDK1是 PDK1 的代码.

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