基于深度学习的预测模型,用于使用心电图数据对心脏再同步治疗反应者的心脏再同步治疗
Hitoshi Mori1, Yuya Fujisaki2, Syunta Higuchi3
1Department of Cardiology, Saitama Medical University International Medical Center, Hidaka, Japan.
Journal of cardiovascular electrophysiology
|December 3, 2025
概括
使用心电图 (ECG) 数据的深度学习模型可以预测心脏再同步治疗 (CRT) 的反应. 这种人工智能方法可以改善患者对CRT的选择,增强心力衰竭管理.
科学领域:
- 心脏病学 心脏病学
- 人工智能的人工智能
- 医疗成像医学成像
背景情况:
- 心脏再同步治疗 (CRT) 是晚期心力衰竭的关键治疗方法.
- 很大一部分患者 (大约. 30%) 不对CRT有反应.
- 预测CRT反应对于优化患者的治疗结果至关重要.
研究的目的:
- 开发和评估用于预测CRT响应的深度学习模型.
- 为了利用植入前心电图 (ECG) 数据进行预测建模.
- 评估不同AI模型架构的有效性.
主要方法:
- 对285名接受CRT植入的患者进行了回顾性分析.
- 基于≥15%的左心室末缩体积减小的CRT响应者的定义.
- 三种模型的开发:ResNet-18 (ECG图像),SSL增强的ResNet-18和LightGBM (时间序列ECG数据).
主要成果:
- 增强SSL的ResNet-18模型显示稳定的性能 (78.5%的准确性,81.3%的PPV).
- 轻GBM模型实现了最高的准确性 (79.4%),而ResNet-18具有最高的PPV (84.2%).
- 模型解释性 (Grad-CAM) 显示了对心电图线索的不同关注,这表明了不同的预测特征.
结论:
- 使用植入前心电图数据的AI模型可以有效地预测CRT响应者.
- 基于图像的深度学习模型在CRT响应预测方面显示出前景.
- 这种人工智能驱动的方法可以增强患者选择和个性化CRT策略.
相关概念视频
Cardiopulmonary Resuscitation III: AED Use
489
Introduction to AEDAn Automated External Defibrillator (AED) is a portable medical device that analyzes the heart's rhythm and, if necessary, delivers an electrical shock to help the heart re-establish an effective rhythm during sudden cardiac arrest (SCA). SCA occurs when the heart suddenly and unexpectedly stops beating, leading to a loss of blood flow to the brain and other vital organs. In such emergencies, time is of the essence, and using an AED, combined with Cardiopulmonary...
489
Correlation between ECG and Cardiac Cycle
11.6K
The electrical signals recorded on an electrocardiogram (ECG) occur before the mechanical processes of contraction and relaxation during the cardiac cycle.
A cardiac action potential originates in the SA node and spreads throughout the atria and the AV node in approximately 0.03 seconds. This results in the P wave in an ECG and triggers atrial contraction. The action potential is then briefly slowed at the AV node, allowing the atria to contract and fill the ventricles with blood before...
A cardiac action potential originates in the SA node and spreads throughout the atria and the AV node in approximately 0.03 seconds. This results in the P wave in an ECG and triggers atrial contraction. The action potential is then briefly slowed at the AV node, allowing the atria to contract and fill the ventricles with blood before...
11.6K
Electrocardiogram
5.3K
An electrocardiogram (ECG or EKG) is a critical diagnostic tool that records the electrical signals produced by the heart during each heartbeat. This recording is achieved through electrodes placed strategically on the arms, legs, and chest. The electrocardiograph amplifies these signals and produces 12 distinct tracings, offering a comprehensive understanding of the heart's electrical activity.
Three major waveforms are present in a typical ECG recording: the P wave, the QRS complex, and...
Three major waveforms are present in a typical ECG recording: the P wave, the QRS complex, and...
5.3K
Pulse rhythm
1.3K
Pulse rhythm refers to the pattern of pulsations within specific intervals, offering valuable insights into the regularity or irregularity of the heart's beats as observed through the pattern of pulsation within specific intervals. A regular pulse exhibits a consistent heart rate with uniform waveforms and pulsation force, variations of which can be classified as normal, weak, or bounding.
Conversely, an irregular pulse pattern is termed dysrhythmia, stemming from disruptions in cardiac...
Conversely, an irregular pulse pattern is termed dysrhythmia, stemming from disruptions in cardiac...
1.3K


