土耳其的糖尿病和慢性病 (DIAKIT):一个横截面队列研究
Mustafa Arici1, Kenan Ates2, Alaattin Yildiz3
1Division of Nephrology, Department of Internal Medicine, Faculty of Medicine, Hacettepe University, Sıhhiye, Ankara, 06230, Turkey. marici@hacettepe.edu.tr.
BMC nephrology
|December 3, 2025
概括
慢性病 (CKD) 影响了土耳其25.1%的糖尿病患者. 早期查,使用尿中的白蛋白与肌素比率 (UACR) 和估计的淋巴细胞过率 (eGFR) 对于及时诊断和治疗至关重要.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 内分泌学 在内分泌学.
- 公共卫生 公共卫生
背景情况:
- 慢性病 (CKD) 是一个重要的全球健康问题,影响全球近10%的成年人.
- 糖尿病患者患CKD的风险更高,需要有针对性的查和管理策略.
研究的目的:
- 确定土耳其糖尿病患者中CKD的患病率.
- 分析该人群中CKD阶段的分布.
- 为了确定与糖尿病患者中CKD存在相关的因素.
主要方法:
- 一项涉及2022年卡帕多西亚队列研究中的1591名糖尿病患者的横截面研究.
- 基于估计的淋巴膜过率 (eGFR) <60mL/min/1.73m2或尿中的白蛋白与肌素比率 (UACR) ≥30 mg/g的CKD诊断.
- 测量UACR是在连续三天早上采集的点滴尿样.
主要成果:
- 在被研究的糖尿病人群中,CKD的患病率为25.1%.
- 在53.8%的CKD患者中,没有降低eGFR的白色素uria存在; 28.1%的CKD患者没有降低eGFR的白色素uria; 18.2%的CKD患者有两种情况.
- 男性 (29.2%) 的CKD患病率高于女性 (22.9%). 与CKD相关的因素包括年龄,男性性别,HbA1c,甘油三,尿酸,C反应蛋白和高血压. 尿酸显示出最强的关联.
- 只有9.4%的CKD患者知道自己的病情.
结论:
- 没有UACR测量,糖尿病患者中大量的CKD病例将被遗漏.
- 使用UACR和eGFR定期查糖尿病患者对于早期发现CKD至关重要.
- 及时诊断和治疗对于减缓糖尿病患者的CKD进展至关重要.
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