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Updated: Jan 9, 2026

Spatial Profiling of Protein and RNA Expression in Tissue: An Approach to Fine-Tune Virtual Microdissection
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有效的空间基因表达造型利用分探针结合和滚动圆放大

Xueqian Xia1, Zhaoxiang Xie1, Yu Yang1

  • 1School of Medicine, Huaqiao University, Xiamen, Fujian, 361021, China.

Small methods
|December 3, 2025
PubMed
概括

一种新的局部RNA成像方法使用分分探针绑定和滚动圆放大 (RCA) 进行空间基因表达概况. 这种技术成功地绘制了小鼠脏中的基因模式,揭示了糖尿病的性别特异性变化.

关键词:
通过RNA成像进行RNA成像.在位杂交RNA在位杂交RNA在现场测序测序.滚动圈放大放大 滚动圈放大放大空间转录学 空间转录学

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相关概念视频

Ribosome Profiling02:24

Ribosome Profiling

Ribosome profiling or ribo-sequencing is a deep sequencing technique that produces a snapshot of active translation in a cell. It selectively sequences the mRNAs protected by ribosomes to get an insight into a cell’s translation landscape at any given point in time.
Applications of ribosome profiling
Ribosome profiling has many applications, including in vivo monitoring of translation inside a particular organ or tissue type and quantifying new protein synthesis levels.
The technique...
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