心理压力与癌症发病率之间的关系:系统性审查和元分析
Sergio Iván Galicia Pacheco1,2,3, Dafina Petrova2,3,4,5, Dunia Garrido1,3
1Faculty of Psychology, University of Granada, Granada, Spain.
Health psychology review
|December 3, 2025
概括
这次审查发现没有一致的证据将心理压力与癌症发病率联系起来. 需要进一步进行高质量的研究,以探索压力和癌症风险之间的复杂关系.
科学领域:
- 心理学是一门科学.
- 在瘤学瘤学.
- 流行病学 流行病学
背景情况:
- 心理压力是癌症的潜在危险因素.
- 以前的研究已经产生了与压力和癌症发病率之间的关联不一致的结果.
研究的目的:
- 系统地审查研究心理压力与癌症发病率之间的关联的前性研究.
- 综合各种癌症类型的压力生活事件和感知压力的证据.
主要方法:
- 19项前性研究的系统审查和元分析.
- 使用NIH工具评估方法质量,使用GRADE评估证据确定性.
- 通过随机效应的元分析合成了危险比率.
主要成果:
- 无论是生活中的压力事件还是感知到的压力都没有显示出与整体癌症风险的一致关联.
- 对于感知到的压力,观察到相互矛盾的结果,指出了保护性和有害的影响,特别是在乳腺癌和结肠直肠癌中.
- 大多数纳入的研究都有局限性,包括未经验证的措施和单个压力评估,导致证据的确定性非常低.
结论:
- 目前的证据并不总是将心理压力与癌症风险联系起来.
- 需要高质量的前性研究与验证的,全面的压力测量,以澄清心理压力在癌症发展中的作用.
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