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Updated: Jan 9, 2026

Establishing a Mouse Model of a Pure Small Fiber Neuropathy with the Ultrapotent Agonist of Transient Receptor Potential Vanilloid Type 1
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Establishing a Mouse Model of a Pure Small Fiber Neuropathy with the Ultrapotent Agonist of Transient Receptor Potential Vanilloid Type 1

Published on: February 13, 2018

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周围阿片类药物耐受性涉及皮肤角质细胞和血小板衍生的生生长因子B型信号传递

Luca Posa, Sophia A Miracle, Kathryn M Albers

    bioRxiv : the preprint server for biology
    |December 3, 2025
    PubMed
    概括

    外周阿片类药物耐受性是疼痛管理中的一个挑战,通过一种涉及皮肤细胞 (角质细胞) 和生长因子的新途径进行介导. 针对血小板衍生生长因子-B (PDGF-B) 和其受体 (PDGFRβ) 可能提供更安全的疼痛缓解.

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