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Updated: Jan 9, 2026

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对比单细胞转录组学揭示了囊性纤维化和初级状腺功能障碍症中共享和独特的分子特征

Nicholas Hadas1, Huihui Xu1, Wang Kyaw Twan1

  • 1Department of Pediatrics, Washington University School of Medicine, St. Louis, Missouri, USA.

bioRxiv : the preprint server for biology
|December 3, 2025
PubMed
概括

囊性纤维化 (Cystic Fibrosis,简称CF) 和初级纤维功能障碍 (Primary Ciliary Dyskinesia,简称PCD) 具有明显的分子差异,影响呼吸系统健康. 了解这些独特的特征是制定针对每个疾病的有针对性的管理策略的关键.

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Cystic fibrosis (CF), an autosomal recessive disorder, significantly affects the function of exocrine glands. This genetically inherited disease is characterized by the production of thick and sticky mucus, which can severely affect various organs and systems in the body.
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