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Updated: Jan 9, 2026

A High Throughput MHC II Binding Assay for Quantitative Analysis of Peptide Epitopes
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针对具有设计T细胞受体和抗体的化物-MHC复合体

Amir Motmaen1,2,3, Kevin M Jude4,5, Nan Wang4,5

  • 1Institute for Protein Design, University of Washington, Seattle, WA, USA.

bioRxiv : the preprint server for biology
|December 3, 2025
PubMed
概括

研究人员开发了ADAPT,这是一个深度学习框架,用于设计T细胞受体 (TCR) 和抗体. 这种方法精确地针对新型癌症免疫疗法和自身免疫性疾病治疗的-MHC (pMHC) 复合体.

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