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Updated: Jan 9, 2026

Author Spotlight: A Model to Study the Systemic and Local Dynamics of CD8+ T Cells During LN Metastasis
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Published on: January 26, 2024

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淋巴毒素驱动的癌细胞根除由瘤杀伤性CD8+ TIL

Hongyan Xie1,2,3, Aiping Jiang1,2,3, Aonkon Dey1,2,3,4

  • 1Mass General Cancer Center, Krantz Family Center for Cancer Research, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.

bioRxiv : the preprint server for biology
|December 3, 2025
PubMed
概括

研究人员发现了一种新的CD8+T细胞子集,该子集对瘤根除至关重要. 这些T细胞利用淋巴毒素β受体 (LTβR) 和干扰素 (IFN) 传感途径杀死癌细胞,提供新的治疗点.

关键词:
细胞死亡是细胞死亡.干扰子干扰子干扰子淋巴毒素是一种淋巴毒素.黑色素瘤是一种黑色素瘤.透到瘤中的淋巴细胞

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