Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Venous Thrombosis I: Introduction01:30

Venous Thrombosis I: Introduction

310
Venous thrombosis, the most common disorder of the veins, involves the formation of a thrombus or blood clot associated with vein inflammation. It can be classified as either superficial vein thrombosis or deep vein thrombosis.Superficial Vein Thrombosis: This involves the formation of a thrombus in a superficial vein, usually the greater or lesser saphenous vein. Though less severe than deep vein thrombosis (DVT), SVT can lead to complications if untreated.Deep Vein Thrombosis (DVT): This...
310
Vascular Resistance01:20

Vascular Resistance

9.9K
Vascular resistance is a critical concept in understanding blood flow dynamics in the circulatory system. It refers to the resistance that blood encounters as it flows through the blood vessels. This resistance is a key factor in determining blood pressure and cardiac workload.
The primary determinants of vascular resistance are vessel diameter, blood viscosity, and vessel length. Among these, vessel diameter plays the most significant role due to the fourth power relationship described by...
9.9K
Viscosity of Fluid01:19

Viscosity of Fluid

1.1K
Viscosity measures the resistance a fluid offers to flow and deformation. It results from internal friction between layers of fluid moving relative to one another. Dynamic viscosity, denoted by the Greek letter mu (μ), quantifies the force needed to move one fluid layer over another. For Newtonian fluids like water and air, the relationship between the shearing stress and the rate of shearing strain is linear, meaning their viscosity remains constant regardless of the applied stress.
1.1K
Viscosity01:17

Viscosity

7.1K
When water is poured into a glass, it falls freely and quickly, whereas if honey or maple syrup is poured over a pancake, it flows slowly and sticks to the surface of the container. This difference in the flow of different kinds of liquids arises due to the fluid friction between the liquid layers and the liquid and the surrounding material. This property of fluids is called fluid viscosity. In this example, water has a lower viscosity than honey and maple syrup.
The SI unit of viscosity is...
7.1K
Surface Tension, Capillary Action, and Viscosity02:57

Surface Tension, Capillary Action, and Viscosity

32.5K
Surface Tension
The various IMFs between identical molecules of a substance are examples of cohesive forces. The molecules within a liquid are surrounded by other molecules and are attracted equally in all directions by the cohesive forces within the liquid. However, the molecules on the surface of a liquid are attracted only by about one-half as many molecules. Because of the unbalanced molecular attractions on the surface molecules, liquids contract to form a shape that minimizes the number...
32.5K
Vascular Spasm01:16

Vascular Spasm

3.3K
The vascular phase, also known as vasospasm, is the initial stage of hemostasis, crucial for preventing excessive bleeding when a blood vessel is injured. After a vessel is cut, nerves in the damaged area trigger pain and other sensory impulses. Simultaneously, the smooth muscles in the vessel wall contract, resulting in a vascular spasm. This contraction reduces the vessel's diameter at the injury site, slowing or stopping blood loss through the vessel wall. Vascular spasms typically last...
3.3K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Light-sensitive Ca<sup>2+</sup> signaling in the mammalian choroid.

Proceedings of the National Academy of Sciences of the United States of America·2024
Same author

Microtubule structures underlying the sarcoplasmic reticulum support peripheral coupling sites to regulate smooth muscle contractility.

Science signaling·2017
查看所有相关文章

相关实验视频

Updated: Jan 9, 2026

In Vitro Model of Physiological and Pathological Blood Flow with Application to Investigations of Vascular Cell Remodeling
07:30

In Vitro Model of Physiological and Pathological Blood Flow with Application to Investigations of Vascular Cell Remodeling

Published on: November 3, 2015

10.0K

血粘度的增加扰乱了微血管流动动力学.

Cristian E Franco, Albert L Gonzales

    bioRxiv : the preprint server for biology
    |December 3, 2025
    PubMed
    概括

    血粘度通过影响内皮细胞信号传递,显著影响毛细血管血流调节. 这表明粘度是微血管输液的关键因素,也是治疗微血管疾病的潜在目标.

    科学领域:

    • 心血管生理学心血管生理学
    • 微循环研究 微循环研究
    • 内皮细胞生物学 内皮细胞生物学

    背景情况:

    • 血液流动的自调节涉及压力诱导的收缩和流量介导的扩张,主要研究在动脉小管中.
    • 对营养交换至关重要的毛细血管水平自我调节的理解较少,特别是内皮细胞,细胞周细胞和血粘度的作用.
    • 血粘度对剪切应力和微血管调节的影响需要进一步定义.

    研究的目的:

    • 为了研究血粘度和剪切应力对毛细血管血流调节的影响,使用活体视网膜制剂.
    • 在高脂肪饮食模型中分析慢性粘度升高对微血管结构,内皮功能和毛细血管 perfusion 的影响.

    主要方法:

    • 采用了 ex vivo 加压视网膜制剂来维持动脉-毛囊连续体.
    • 检查了内皮细胞和壁细胞活动,以应对改变的内粘度和剪切应力.
    • 在高脂肪饮食模型中评估了微血管重塑,内皮反应能力和毛细血管输液.

    主要成果:

    • 增加粘度增强了内皮细胞的活性,并通过氧化抑制了周围细胞/平滑肌肉细胞通过氧化发出信号.
    • 慢性粘度升高导致了动脉状动脉的重塑,但损害了剪切感应和毛细血管在过渡和毛细血管段的招募.
    • 高脂肪饮食降低了基线毛细血管输液,并取消了依赖粘度的调制,表明基于剪切的控制失去了.

    更多相关视频

    Endothelialized Microfluidics for Studying Microvascular Interactions in Hematologic Diseases
    11:08

    Endothelialized Microfluidics for Studying Microvascular Interactions in Hematologic Diseases

    Published on: June 22, 2012

    16.6K
    Micro-particle Image Velocimetry for Velocity Profile Measurements of Micro Blood Flows
    07:53

    Micro-particle Image Velocimetry for Velocity Profile Measurements of Micro Blood Flows

    Published on: April 25, 2013

    17.7K

    相关实验视频

    Last Updated: Jan 9, 2026

    In Vitro Model of Physiological and Pathological Blood Flow with Application to Investigations of Vascular Cell Remodeling
    07:30

    In Vitro Model of Physiological and Pathological Blood Flow with Application to Investigations of Vascular Cell Remodeling

    Published on: November 3, 2015

    10.0K
    Endothelialized Microfluidics for Studying Microvascular Interactions in Hematologic Diseases
    11:08

    Endothelialized Microfluidics for Studying Microvascular Interactions in Hematologic Diseases

    Published on: June 22, 2012

    16.6K
    Micro-particle Image Velocimetry for Velocity Profile Measurements of Micro Blood Flows
    07:53

    Micro-particle Image Velocimetry for Velocity Profile Measurements of Micro Blood Flows

    Published on: April 25, 2013

    17.7K

    结论:

    • 动脉小管和毛细血管之间的自我调节机制显著不同,粘度依赖的内皮信号对毛细血管流动至关重要.
    • 血粘度是微血管 perfusion 的一个重要的调节器.
    • 血粘度可以作为微血管疾病的生物标志物和治疗标.