用数字技术量化医院环境中的睡眠-觉醒节奏
Carsten Skarke1,2, Nadim El Jamal1, Michael V Genuardi2
1Institute for Translational Medicine and Therapeutics (ITMAT), University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA.
medRxiv : the preprint server for health sciences
|December 3, 2025
概括
住院会扰乱患者的自然睡眠-觉醒周期. 在术后护理期间,光,声音和温度的干扰会对恢复和认知功能产生负面影响.
科学领域:
- 循环生物学的日间运行时间.
- 睡眠的药物 睡眠的药物
- 术后护理 术后护理
背景情况:
- 术后临床护理环境往往会扰乱患者的自然昼夜节律.
- 这种昼夜失调可能会对患者的健康结果和康复产生负面影响.
研究的目的:
- 在术后护理环境中量化环境破坏因素.
- 评估这些干扰对患者行为生理节奏和认知功能的影响.
主要方法:
- 采集了180万个数据点,使用了13名心脏手术患者的11个远程传感器.
- 监测了手术前,住院和出院后的情况.
- 评估环境因素 (光,声音,温度),生理节奏 (心率变化) 和认知功能.
主要成果:
- 医院环境经常出现夜间活动,过度噪音和温度调节不足.
- 观察到显著的行为和生理节律的破坏和相位转移,包括增加的夜间清醒 (10.7%至34.8%).
- 认知功能得分下降,31%的患者经历过渡性轻度损伤.
结论:
- 手术后护理环境存在显著的昼夜和昼夜干扰因素.
- 这些干扰与生理节奏和认知功能受损有关.
- 这些发现支持了对减轻环境破坏因素和改善患者治疗结果的干预措施的需求.
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