核TDP-43的丧失会损害微细胞类细胞中的脂质代谢

Khushbu Kabra1, Dallin Dressman2, Ryan Talcoff2

  • 1Columbia University Irving Medical Center.

Research square
|December 3, 2025
PubMed
概括

肌缩性侧面硬化症 (ALS) 中的TDP-43蛋白质功能障碍改变了微质甘油三代谢,影响了它们的炎症和细胞功能. 针对这种途径可能为ALS患者提供新的治疗策略.

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