抑制素依赖的DNA修复和氧化应激反应会损害DIPG细胞的存活率

Sarah A King1, Rana Rheem1, Kathryn M Spitler1

  • 1Free Radical and Radiation Biology Program, Department of Radiation Oncology, Holden Comprehensive Cancer Center, University of Iowa, Iowa City, IA, USA.

Research square
|December 3, 2025
PubMed
概括

丁醇是一种新型治疗药物,通过增加氧化应激和损害DNA修复,选择性地降低了扩散内在庞丁质瘤 (DIPG) 细胞的存活率. 这种儿童脑瘤药物显示出增强治疗策略的前景.

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