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Updated: Jan 9, 2026

Evaluation of Exon Inclusion Induced by Splice Switching Antisense Oligonucleotides in SMA Patient Fibroblasts
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Published on: May 11, 2018

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维生素B12可以通过脂重塑来缓解结合体病变

Adam Antebi1, Wenming Huang1, Jonathan Kölschbach1

  • 1Max Planck Institute for Biology of Ageing.

Research square
|December 3, 2025
PubMed
概括

由PUF60突变引起的Verheij综合征扰乱了单碳代谢和脂合成. 维生素B12 (VB12) 补充剂通过恢复代谢平衡和生长来挽救这些缺陷,提供了一个潜在的治疗策略.

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