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Updated: Jan 9, 2026

Exploring Sequence Space to Identify Binding Sites for Regulatory RNA-Binding Proteins
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由RNA诱导的PRC2抑制取决于结合RNA的序列

Jiarui Song1,2,3, Liqi Yao1, Anne R Gooding1,2,3

  • 1Department of Biochemistry, University of Colorado Boulder, Boulder, CO 80303, USA.

Research square
|December 3, 2025
PubMed
概括

聚合物抑制复合物2 (PRC2) 结合了各种RNA,但只有那些诱导PRC2二分化的人抑制了它的甲基转移酶活性. RNA序列决定PRC2的调节,影响表观遗传基因沉默.

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