压力的微生物学:一个系统的审查
Dmitry Shelepenko1, Beatriz Jardim2, Luís M Almeida3
1Department of Plastic and Reconstructive Surgery and Burns Unit, Coimbra Local Health Unit, Coimbra, PRT.
Cureus
|December 3, 2025
概括
这份综述确定了压力中常见的细菌,发现了金黄色葡萄球菌,肠杆菌和伪菌. 它们是最常见的. 这些发现支持针对这些复杂伤口的经验性抗生素治疗.
科学领域:
- 传染性疾病 传染性疾病
- 伤口护理 伤口护理
- 微生物学 微生物学
背景情况:
- 压力是复杂的伤口,通常因感染而复杂化.
- 了解这些的微生物环境对于有效治疗至关重要.
- 目前的诊断和治疗策略面临的挑战是由于动态的微环境.
研究的目的:
- 描述微生物在压力中的分布.
- 评估研究异质性,并比较侵入性和非侵入性采样技术之间的微生物产量.
- 为压力感染的抗菌药物管理策略提供信息.
主要方法:
- 对报告压力的微生物学数据的研究进行了系统审查.
- 在PubMed,Embase和Cochrane图书馆进行了搜索,直到2025年1月.
- 使用已建立的框架 (ROBINS-I V2,ROBINS-E,ROB 2) 评估了偏差风险.
主要成果:
- 分析了28项研究,包括1473名患者和1682名压力.
- 黄金葡萄球菌 (39.7%),Corynebacterium spp. 这种细菌. 大肠杆菌 (28.8%) 和大肠杆菌 (23.1%) 是最常被隔离的微生物.
- 在研究中观察到显著的异质性,在拭子和活检采样方法之间微生物产量存在差异.
结论:
- 尽管异质,重复性病原体的核心组包括金黄色葡萄球菌,肠杆菌,菌株菌株菌株菌株菌株菌株菌株菌株菌株菌株菌株菌株菌株菌株, Pseudomonas spp. 和 Bacteroides spp. 主导压力的植物.
- 需要采样和报告的标准化协议来改善解释.
- 这些发现为实证抗微生物治疗提供了一个框架,需要通过前性受控试验进行进一步调查.
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