全球患病率,区域分布和分裂性尾炎的人口结构模式:系统性审查和元分析
Younis Al-Mufargi1,2, Nisreen Al-Busaidi3, Haya Al Maamari3
1General Surgery, Medical City for Military and Security Services, Muscat, OMN.
Cureus
|December 3, 2025
概括
分裂性尾炎 (SA) 影响全球1.84%,在特有地区和非洲的患病率更高. 这种寄生虫感染是尾炎的重要原因,特别是在中低收入国家,显示出上升趋势和男性占主导地位.
科学领域:
- 寄生虫学的寄生虫学
- 胃肠病学 胃肠病学
- 流行病学 流行病学
背景情况:
- 分裂性尾炎 (SA) 是一个被诊断不足的疾病,因为它在临床环境中很罕见.
- 缺乏准确的全球流行和分布数据,阻碍了有针对性的公共卫生干预.
- 了解SA的流行病学对于管理其在特有和非特有地区的影响至关重要.
研究的目的:
- 系统地审查和分析现有文献,以确定分裂性尾炎 (SA) 的全球患病率和分布模式.
- 确定影响SA流行的地理,经济和时间因素.
- 评估SA和尾炎之间的关联.
主要方法:
- 根据PRISMA指南进行了系统审查和元分析.
- 搜索了五个数据库,查找观察性队列研究报告从尾切除标本中组织学证实SA病例.
- 数据提取和质量评估 (JBI检查清单) 由两个独立审查员进行,随后进行随机效应元分析和子组分析.
主要成果:
- 在24项研究 (41,301个标本) 中,SA的全球综合流行率为1.84%, (95% CI:1.13%-2.71%).
- 流行率在特有地区 (2.67%) 与非特有地区 (0.16%) 相比显著更高,非洲地区的流行率最高 (3.22%).
- 2015年以后,SA的患病率增加,男性占主导地位 (2.78:1比),91.92%的确诊病例表现出尾炎.
结论:
- 轮状尾炎是流行地区尾炎的重要原因,尽管全球轮状尾炎发病率正在下降.
- 建议对尾切除样本进行例行组织病理学检查,以确定确切的诊断.
- 持续控制和消除杆菌病的努力至关重要,以减少SA的负担.
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