患者对精神分裂症数字治疗方法的看法:对负面症状应用程序的定性评估
Arti Gandhi1, Ruth L Firmin2, Lauren Luther3
1Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, CT 06877, United States.
Schizophrenia bulletin open
|December 3, 2025
概括
一个针对精神分裂症的新型数字治疗应用程序在改善应对能力和动机方面表现有前途. 患者反突出了可用性和好处,指导了未来的应用程序开发,以获得更好的结果.
科学领域:
- 精神病学是一个精神病学.
- 数字治疗学数字治疗学
- 精神分裂症治疗 治疗精神分裂症
背景情况:
- 精神分裂症的负面症状显著损害了功能结果.
- 目前针对精神分裂症负面症状的治疗方法的疗效有限.
- CT-155是一种基于智能手机的新型数字治疗 (DTx) 治疗精神分裂症,利用心理社会干预.
研究的目的:
- 为了探索CT-155 (CT-155 beta) 的测试版用户体验.
- 识别可用性,促进者和应用程序使用障碍,以实现长期有效性.
- 收集患者的反,以优化数字治疗方法.
主要方法:
- 对42名参与者的半结构面试进行了定性分析.
- 探索性,多中心,7周,单臂,开放标签研究 (NCT05486312).
- 主题分析以确定可用性,好处和挑战的模式.
主要成果:
- 参与者发现该应用程序可访问和易于导航,无论数字体验如何.
- 报告的好处包括改善应对能力,动机,社交技能和结构化的日常生活.
- 实施考虑涉及技术问题,个性化需求和症状影响.
结论:
- 早期的见解支持CT-155 beta的可接受性和可用性.
- 用户反为未来的开发和应用程序更新提供了方向.
- 结果为应用程序的更新提供了信息,该应用程序在随后的第三阶段研究中进行了评估.
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