在HFrEF和HFpEF之间比较肉类的流行率和预后特征:系统性审查和元分析
Weizhu Xiong1, Jun Yang2, Xinbin Zhou1
1Department of Cardiology, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, Zhejiang, China.
Frontiers in cardiovascular medicine
|December 3, 2025
概括
在心力衰竭与减少喷射分数 (HFrEF) 和保存喷射分数 (HFpEF) 现型之间,肉症的患病率不同,但喷射分数类型不会影响心力衰竭患者的肉症患病率或预后.
科学领域:
- 心脏病学 心脏病学
- 老年病的医生 老年病的医生
- 内部医学 内部医学
背景情况:
- 萨科佩尼亚是心力衰竭 (HF) 中已知的并发症.
- 关于不同高频射出分数表型 (HFrEF与HFpEF) 中的萨尔科佩尼亚患病率存在有限的研究.
- 这一元分析调查了HFrEF和HFpEF患者的肉类的患病率和预后影响.
研究的目的:
- 确定和比较患有心力衰竭与减少喷射分数 (HFrEF) 和心力衰竭与保存喷射分数 (HFpEF) 的患者中缩症的患病率.
- 探索这些独特的HF表型中与sarcopenia相关的预后结果.
主要方法:
- 在PubMed,Cochrane和Embase数据库进行了系统的文献搜索,截至2025年2月.
- 包含的研究报告了HF患者具有定义的射出分数表型的sarcopenia患病率或预后.
- 用随机效应模型进行了元分析,以综合来自20项纳入研究的数据.
主要成果:
- 在HFrEF中,聚合的肉类的患病率为35%,在HFpEF中为28%.
- 观察到的区域差异:亚洲的HFrEF流行率更高,欧洲的HFpEF流行率更高.
- 分析显示,HFrEF和HFpEF患者之间在sarcopenia患病率 (RR 1.12) 或预后 (HR 1.57) 中没有显著差异.
结论:
- 虽然在HFrEF和HFpEF之间,肉类的流行病学流行率有所不同,但喷射分数表型并没有显著地影响HF中肉类的流行率.
- 这项研究发现,射出分数表型与萨尔科佩尼亚HF患者的不良结果之间没有显著的关联.
相关概念视频
01:17Pathophysiology of Heart Failure
2.7K
Heart failure (HF) is a progressive syndrome involving ventricles that leads to inadequate cardiac output. It can be classified based on location and output or ejection fraction. Ejection fraction (EF) is an essential measurement in the diagnosis and surveillance of HF. Reduced EF corresponds to systolic heart failure (HFrEF). However, HF with preserved ejection fraction (HFpEF) is becoming increasingly prevalent. Also known as diastolic HF, this form of HF is related to aging. The...
2.7K
01:22Heart Failure VI: Adjunct Therapies
235
Additional therapies for treating patients with heart failure (HF) may include procedural interventions, supplemental oxygen, the management of sleep disorders, and nutritional therapy.Procedural InterventionsImplantable Cardioverter-Defibrillator: For patients at risk of life-threatening arrhythmias due to severe left ventricular dysfunction, an Implantable Cardioverter-Defibrillator (ICD) can detect and terminate these arrhythmias, preventing sudden cardiac death and improving survival rates.
235
01:29Heart Failure II: Pathophysiology
685
Systolic Heart Failure and Compensatory MechanismsSystolic heart failure (also termed HFrEF, Heart Failure with Reduced Ejection Fraction) is the most prevalent type of heart filure. It results in a decreased volume of blood being pumped from the ventricle. The aortic arch and carotid sinuses have baroreceptors that detect reduced blood pressure, triggering the sympathetic nervous system (SNS) to release epinephrine and norepinephrine. Initially, this response aims to boost heart rate and...
685
01:30Heart Failure V: Medical Management
200
Medical Management of Acute Decompensated Heart Failure (ADHF)The primary goals of therapy for patients hospitalized with acute decompensated heart failure (ADHF) include:Relieving symptomsOptimizing volume statusSupporting oxygenation and ventilationMaintaining cardiac output (CO) and end-organ perfusionIdentifying and addressing the cause of ADHFPreventing complicationsProviding patient education on factors precipitating HF exacerbationPlanning for dischargeOngoing monitoring and assessment...
200
01:30Heart Failure IV: Classification and Diagnostic Evaluation
295
Heart failure can be classified in various ways, with the most common classifications based on physical activity limitations, disease progression, severity, and treatment strategies.The Functional Classification of Heart Failure divides patients into four categories based on physical activity limitation due to symptom burden.Class I: Patients in this class have cardiac disease but no physical activity limitations. Ordinary activities like walking, climbing stairs, or routine tasks do not cause...
295
01:27Heart Failure I: Introduction
670
Heart failure refers to a clinical syndrome caused by structural or functional cardiac disorders that prevent the heart from pumping an adequate amount of blood to meet the body's metabolic needs. This condition often arises from myocardial infarction or ischemia, leading to decreased cardiac output, reduced tissue perfusion, impaired gas exchange, fluid volume imbalance, and decreased functional ability.Heart failure can result from disruptions in the mechanisms that regulate cardiac output...
670