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停止使用的趋势和边界肌肉缩研究

Shenghui Wu¹, Yu Miao², Jiong Mei²

¹Department of Orthopedic Surgery, Fujian Medical University Union Hospital, Fujian, China.

Frontiers in public health

|December 3, 2025

概括

对失效肌肉缩 (DMA) 的研究正在迅速增加,重点是氧化应激和衰老等分子机制. 运动和葡萄糖皮质类药物对肌肉恢复有前途,而肌肉肌肉是研究的关键领域.

科学领域:

生物医学科学生物医学科学
生理学生理学生理学
分子生物学分子生物学

背景情况:

消耗肌肉缩 (DMA) 是一个重要的生理挑战.
了解DMA的进展和当前的研究趋势对于开发有效的干预措施至关重要.

研究的目的:

调查停止使用肌肉缩 (DMA) 的进展和状态.
识别和突出目前热门的研究领域和趋势在DMA.

主要方法:

在PubMed上从2010年到2024年进行了全面的文献搜索.
用R软件 (4.2.0版本) 进行了图书统计分析.

主要成果:

总共发表了689篇与DMA相关的文章,显示了研究的持续增长.
美国在出版方面处于领先地位,犹他大学是最具生产力的机构.
关键的研究术语包括"氧化应激"",衰老"",运动"",蛋白质合成"",线粒体"",炎症"",Murf1"",底部肌肉"",Foxo3"",ROS"和"糖皮质激素".

结论:

研究越来越强调DMA的分子机制,包括氧化应激,衰老,蛋白质合成,线粒体功能和炎症.
确定Murf1和Foxo3在DMA过程中至关重要.
运动和葡萄糖皮质类药物是肌肉恢复的关键,而肌肉肌肉是主要的焦点.

关键词:

在PubMed上发现了这一点.R 软件软件软件软件软件文献计量分析的分析不使用肌肉缩肌肉缩视觉化视觉化

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