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Updated: Jan 6, 2026

A Combined 3D Tissue Engineered In Vitro/In Silico Lung Tumor Model for Predicting Drug Effectiveness in Specific Mutational Backgrounds
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瘤外周硬度通过调节FIS1依赖的线粒细胞衰变通过调节HCC临床前模型中的伦瓦替尼抗性来调节伦瓦替尼抗性

Kunjin Wu1,2, Jing Li1,2, Yunong Fu3

  • 1Department of Hepatobiliary Surgery and Liver Transplantation, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710004, Shaanxi, China.

JHEP reports : innovation in hepatology
|December 3, 2025
PubMed
概括

在肝细胞癌 (HCC) 中的瘤硬性通过促进线粒体分裂和线粒体分裂来降低伦瓦替尼的疗效. 用原酶准矩阵刚度与伦瓦提尼布有协同作用,克服耐药性并改善治疗结果.

关键词:
肝细胞癌是肝细胞癌.伦瓦替尼的敏感性 伦瓦替尼的敏感性机械微环境 机械微环境机械医学 机械医学线粒体裂变的线粒体裂变线粒细胞衰变 - - 线粒细胞衰变 (mitophagy) 是一种

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