Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Myasthenia Gravis: Overview and Treatment01:20

Myasthenia Gravis: Overview and Treatment

2.7K
Myasthenia gravis is a neuromuscular transmission disorder characterized by weakness and increased fatigability of skeletal muscles. It is an autoimmune disease affecting approximately one in 2000 people, where antibodies against the α1 subunit of nicotinic acetylcholine receptors are produced.
These antibodies interfere with the function of the nicotinic receptors in three ways: by binding to the receptor and disrupting acetylcholine binding; by causing cross-linking of receptors which...
2.7K
Myasthenia Gravis: Diagnostic Tests01:15

Myasthenia Gravis: Diagnostic Tests

1.9K
Myasthenia gravis is an autoimmune condition affecting neuromuscular transmission, causing generalized weakness in skeletal muscles. Initial diagnoses rely on patients' signs, symptoms, and medical history. The challenge lies in distinguishing myasthenia from other muscular dystrophies. An important diagnostic feature is the significant improvement of symptoms after administering anticholinesterase inhibitors.
The edrophonium test is a diagnostic tool for myasthenia gravis. It involves...
1.9K
Disorders of the Skeletal Muscle01:28

Disorders of the Skeletal Muscle

1.7K
The clinical conditions affecting the skeletal muscle tissue are broadly categorized as musculoskeletal and neuromuscular disorders.
Musculoskeletal disorders
Musculoskeletal disorders involve injuries and conditions affecting the skeletal muscles and associated connective tissues. These disorders can arise from acute biomechanical stresses or chronic overuse and can occur across different age groups. Common injuries include sprains, fractures, and muscular strains, often resulting from...
1.7K
Chemical Synapses01:26

Chemical Synapses

11.1K
Chemical synapses are specialized sites between two neurons or between a neuron and a non-neuronal cell like a muscle, glandular or sensory cell.
Because chemical synapses depend on the release of neurotransmitter molecules from synaptic vesicles to pass on their signal, there is an approximately one millisecond delay between when the axon potential reaches the presynaptic terminal and when the neurotransmitter leads to opening of postsynaptic ion channels. Additionally, this signaling is...
11.1K
Skeletal Muscle Relaxants: Therapeutic Uses01:31

Skeletal Muscle Relaxants: Therapeutic Uses

859
Skeletal muscle relaxants are used to relax muscle tone and alleviate painful muscle contractions. However, the choice of skeletal muscle relaxants depends on the duration of the surgical procedure in order to minimize potential side effects. Skeletal muscle relaxants like neuromuscular blocking agents [NMBAs] are commonly employed as adjuvants alongside general anesthetics in clinical settings. NMBAs are also used to maintain controlled ventilation during surgery of the larynx or pharynx...
859

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Validation of the International Weed Genomics Consortium genome annotation pipeline through reannotation of the model species Arabidopsis thaliana.

The plant genome·2026
Same author

Range of detection and naturalistic search performance for spotted lanternfly (<i>Lycorma delicatula</i>) egg masses.

PeerJ·2026
Same author

Heterogeneity of Treatment Effects Across Nine Glucose-Lowering Drug Classes in Type 2 Diabetes: Extension of the LEGEND-T2DM Network Study.

Diabetes, obesity & metabolism·2026
Same author

Semaglutide and Neovascular Age-Related Macular Degeneration Among Adults with Type 2 Diabetes: An OHDSI Network Study.

Ophthalmology·2026
Same author

VO: The Vaccine Ontology.

Scientific data·2026
Same author

Tumor Necrosis Factor Inhibitor Treatment and Persistence Patterns in the Peripregnancy Period in Patients With Inflammatory Autoimmune Diseases.

ACR open rheumatology·2026

相关实验视频

Updated: Jan 9, 2026

A Battery of Motor Tests in a Neonatal Mouse Model of Cerebral Palsy
10:02

A Battery of Motor Tests in a Neonatal Mouse Model of Cerebral Palsy

Published on: November 3, 2016

25.4K

描述围产期治疗模式和结局在严重肌痛性肌痛症.

Melanie H Jacobson1, Rupa Makadia1, Ashley E L Anderson2

  • 1Johnson & Johnson, Horsham, Pennsylvania, USA.

Muscle & nerve
|December 3, 2025
PubMed
概括

在肌痛性硬化症 (MG) 中的怀孕与子宫前,剖腹产,早产和妊娠年龄相对小的婴儿的风险增加有关. 许多MG患者在怀孕期间没有接受治疗,这凸显了护理方面的潜在差距.

关键词:
疾病负担的疾病负担.肌痛性骨髓灰质炎 (Myasthenia Gravis) 是一个严重的疾病.围产期的时间 围产期的时间怀孕 怀孕 怀孕 怀孕 怀孕治疗模式 治疗模式

更多相关视频

Home-Based Monitor for Gait and Activity Analysis
07:24

Home-Based Monitor for Gait and Activity Analysis

Published on: August 8, 2019

7.2K
Muscle Velocity Recovery Cycles to Examine Muscle Membrane Properties
08:27

Muscle Velocity Recovery Cycles to Examine Muscle Membrane Properties

Published on: February 19, 2020

14.7K

相关实验视频

Last Updated: Jan 9, 2026

A Battery of Motor Tests in a Neonatal Mouse Model of Cerebral Palsy
10:02

A Battery of Motor Tests in a Neonatal Mouse Model of Cerebral Palsy

Published on: November 3, 2016

25.4K
Home-Based Monitor for Gait and Activity Analysis
07:24

Home-Based Monitor for Gait and Activity Analysis

Published on: August 8, 2019

7.2K
Muscle Velocity Recovery Cycles to Examine Muscle Membrane Properties
08:27

Muscle Velocity Recovery Cycles to Examine Muscle Membrane Properties

Published on: February 19, 2020

14.7K

科学领域:

  • 神经学 神经学
  • 产科 产科 产科 产科 产科
  • 围产期健康 围产期健康

背景情况:

  • 骨髓灰质炎 (MG) 是一种罕见的自身免疫性疾病,影响神经肌肉结节.
  • 由于研究规模较小,对MG患者的妊娠结果和治疗模式的数据有限.
  • 了解这些结果对于优化母婴护理至关重要.

研究的目的:

  • 估计由MG复杂的怀孕中关键的周产期和婴儿结局的患病率.
  • 描述整个产周期内MG的治疗模式.
  • 确定孕妇MG患者改善管理策略的潜在领域.

主要方法:

  • 使用美国大型医疗保险索赔数据库 (Merative MarketScan CCAE) 的回顾性队列研究.
  • 确定18-49岁女性的怀孕情况,将母婴记录与婴儿记录联系起来.
  • 基于住院或门诊诊断码的MG定义;结果流行率的计算和治疗类的总结.

主要成果:

  • MG怀孕显示出更高的孕前率 (10.7%vs7.1%),剖腹产 (42.9%vs36.7%),早产 (18.0%vs9.9%),以及对于妊娠年龄的小 (4.3%vs1.7%).
  • 显著比例的MG患者在怀孕前6个月 (54.3%),怀孕期间 (61.2%) 和分娩后 (57.8%) 没有接受治疗.
  • 在接受治疗的患者中,在怀孕期间观察到新开始服用乙胆酶抑制剂 (21.8%) 或皮质类固醇 (33.1%) 的情况.

结论:

  • 骨髓灰质炎与不良周产期和婴儿结局的患病率增加有关.
  • 围产期内MG的治疗不足是常见的,这表明需要更好的管理方案.
  • 治疗模式各不相同,这表明可能需要对患有MG的孕妇进行更一致和及时的干预.