越来越频繁的肺前列腺血栓炎由A组链球菌更严重,而不是通过链球菌肺炎
Catarina Miguel Boto1, Sofia Raposo Carneiro1, Margarida Ramalho2
1From the Pediatric Infectious Diseases Unit, Hospital Dona Estefânia, ULS São José, Academic Clinical Centre of Lisbon, Lisbon, Portugal.
The Pediatric infectious disease journal
|December 3, 2025
概括
细菌肺炎菌血清型3仍然是儿童复杂肺炎的主要原因. 然而,在2023年观察到A组链球菌 (GAS) 病例的增加,特别是M1UK亚系.
科学领域:
- 儿童传染病 儿童传染病
- 细菌学 细菌学是一门学科.
- 流行病学 流行病学
背景情况:
- 肺炎 estreptococcus (Sp) 是复杂的肺炎的首要原因,并带有副肺喷液/多叶脉 (PPE/PE).
- 在2022年,儿童的A型链球菌 (GAS) 复杂性肺炎的增加被注意到.
研究的目的:
- 审查和比较儿童中Sp和GAS复杂性肺炎的临床特征.
- 为了确定葡萄牙儿科复杂肺炎的趋势.
主要方法:
- 关于在2018年至2023年期间入院于葡萄牙四家三级医院的128例患有Sp或GAS并发性肺炎的儿科病例的回顾性审查.
- 使用分子方法和从肺部液或血液中培养的病原体鉴定.
- 临床特征的分析,包括皮疹,喉炎,败血症休克,前素水平,ICU入院和机械通风.
主要成果:
- 107例是由Sp引起的,21例是由GAS引起的,在2023年,个人防护设备/人体防护设备的增加显著.
- 患有GAS PPE/PE的儿童更有可能出现皮疹,喉炎,败血症,并需要接受ICU和机械通风治疗.
- 肺炎链球菌血清型3是最常见的Sp血清型,GAS M1UK亚系在2023年起的病例中被确定.
结论:
- 在葡萄牙,Streptococcus pneumoniae血清型3仍然是儿科PPE/PE的主要病原体.
- 气体PPE/PE病例的增加与M1UK亚系的扩张有关.
- 在患有特定临床症状的儿童中,应该怀疑GAS,及时治疗对于改善结果至关重要.
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