辐射诱导的关节下动脉狭窄症具有不同的损伤复杂性,需要重新血管化
Grigorios Korosoglou1, Dittmar Böckler2, Eric Secemsky3
1GRN Hospital Weinheim, Cardiology & Vascular Medicine, Eberbach, Germany; GRN Hospital Eberbach, Cardiology & Vascular Medicine, Weinheim, Germany; Cardiovascular Imaging Center, Hector Foundation, Weinheim, Germany.
JACC. Case reports
|December 3, 2025
概括
放射治疗可能导致动脉样硬化加速,导致严重的血管问题,如上肢缺血症. 早期检测和监测对于有放射治疗史的患者至关重要.
科学领域:
- 血管医学 血管医学
- 干预心脏病学 干预心脏病学
- 在瘤学瘤学.
背景情况:
- 辐射诱导动脉样硬化是一种未被认可的临床问题.
- 加速动脉样硬化是放射治疗的一个已知的后果.
- 这种情况可以在癌症治疗后多年表现出来.
研究的目的:
- 呈现两例辐射诱导的关节下动脉病变,导致上肢缺血.
- 突出这些罕见病例管理的诊断和治疗挑战.
- 强调对有放射治疗病史的患者进行监测的重要性.
主要方法:
- 两名患者的病例报告,在放射治疗后出现延迟上肢缺血.
- 诊断血管造影和血管内超声波 (IVUS) 来表征关节下动脉病变.
- 血管内治疗包括血管造形术,支架安置和血管内利索.
主要成果:
- 两位患者均出现显著的关节下动脉狭窄/闭塞.
- IVUS提供了关于病变化和设备尺寸的关键信息.
- 达到了成功的内血管治疗,第二名患者需要为严重化而进行石灰.
结论:
- 放射治疗可以导致严重的,治疗几年后的焦点动脉样硬化.
- 血管内超声波对于评估和指导辐射诱导病变的治疗是无价的.
- 患有放射治疗史的患者可能受益于对加速动脉样硬化进行长期临床和成像监测.
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