Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Ribosome Profiling02:24

Ribosome Profiling

4.0K
Ribosome profiling or ribo-sequencing is a deep sequencing technique that produces a snapshot of active translation in a cell. It selectively sequences the mRNAs protected by ribosomes to get an insight into a cell’s translation landscape at any given point in time.
Applications of ribosome profiling
Ribosome profiling has many applications, including in vivo monitoring of translation inside a particular organ or tissue type and quantifying new protein synthesis levels.
The technique...
4.0K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Regulation of Myogenic Cell Apoptosis, UPS, and Autophagy During Mammalian Skeletal Myogenesis.

Cells·2026
Same author

Identifying hot-spot pathways in fishery science and technology innovation through temporal heterogeneous graph neural networks.

Scientific reports·2026
Same author

Nutritional dynamics and untargeted metabolomics reveal breed and lactation-dependent shifts in goat milk composition: from colostrum to mature milk.

Food chemistry: X·2026
Same author

A scaffold-degradable single-rivet ASD occluder with amplatzer-like design: a multicenter randomized controlled trial.

Cardiovascular intervention and therapeutics·2026
Same author

Dynamic-weighing grain mass flow sensing for reliable in-field yield monitoring in combine harvesters.

Frontiers in plant science·2026
Same author

Super-Enhancer-Associated Gene 3-Hydroxybutyrate Dehydrogenase 1 Increases Intramuscular Fat Deposition of Yaks (<i>Bos grunniens</i>).

Foods (Basel, Switzerland)·2026
Same journal

Meet Our Editorial Board-Genesis. An Interview With Anna Di Gregorio, New York University, New York, USA.

Genesis (New York, N.Y. : 2000)·2026
Same journal

Multiplexed Retinoic Acid Signal Reporters for In Vivo and In Vitro Use.

Genesis (New York, N.Y. : 2000)·2026
Same journal

Generation and Characterization of Twist1 Acetyl-Mimic and Acetyl-Deficient Mouse Models.

Genesis (New York, N.Y. : 2000)·2026
Same journal

Phylogenetic Comparison and Splice Site Conservation of the Animal SMNDC1 Gene Family.

Genesis (New York, N.Y. : 2000)·2026
Same journal

Pvr and Pvf2 Are Essential for Valve Cell Differentiation in the Larval Drosophila Heart.

Genesis (New York, N.Y. : 2000)·2026
Same journal

Efficient Gene Expression System in Medaka Embryos Enables Functional Characterization of nt5c1a Paralogs Involved in Inosine Monophosphate Metabolism.

Genesis (New York, N.Y. : 2000)·2026
查看所有相关文章

相关实验视频

Updated: Jan 9, 2026

Dissection of Drosophila melanogaster Flight Muscles for Omics Approaches
08:33

Dissection of Drosophila melanogaster Flight Muscles for Omics Approaches

Published on: October 17, 2019

12.7K

骨肌肉系统的转录基因分析,比较使用scRNA-Seq的牛,人类和小鼠.

Cuicui Cai1,2,3, Xueyao Yang2, Hui Wang1

  • 1Key Laboratory of Qinghai-Tibetan Plateau Animal Genetic Resource Reservation and Utilization, Sichuan Province and Ministry of Education, Southwest Minzu University, Chengdu, China.

Genesis (New York, N.Y. : 2000)
|December 3, 2025
PubMed
概括
此摘要是机器生成的。

这项研究使用单细胞转录组学绘制牛骨肌肉发育图,揭示了与人类和小鼠相比保存的多能性和物种特异性差异.

关键词:
牛肉类的牛肉类的牛肉类.进行比较转录基因分析.人类 人类 人类 人类 人类 人类 人类这里是鼠标鼠标鼠标鼠标鼠标鼠标.在 scRNA-seqq 中.这是骨肌肉的骨架肌肉.

更多相关视频

Cryosectioning of Contiguous Regions of a Single Mouse Skeletal Muscle for Gene Expression and Histological Analyses
08:17

Cryosectioning of Contiguous Regions of a Single Mouse Skeletal Muscle for Gene Expression and Histological Analyses

Published on: December 12, 2016

16.5K
Laser Capture Microdissection of Mouse Embryonic Cartilage and Bone for Gene Expression Analysis
09:20

Laser Capture Microdissection of Mouse Embryonic Cartilage and Bone for Gene Expression Analysis

Published on: December 18, 2019

7.5K

相关实验视频

Last Updated: Jan 9, 2026

Dissection of Drosophila melanogaster Flight Muscles for Omics Approaches
08:33

Dissection of Drosophila melanogaster Flight Muscles for Omics Approaches

Published on: October 17, 2019

12.7K
Cryosectioning of Contiguous Regions of a Single Mouse Skeletal Muscle for Gene Expression and Histological Analyses
08:17

Cryosectioning of Contiguous Regions of a Single Mouse Skeletal Muscle for Gene Expression and Histological Analyses

Published on: December 12, 2016

16.5K
Laser Capture Microdissection of Mouse Embryonic Cartilage and Bone for Gene Expression Analysis
09:20

Laser Capture Microdissection of Mouse Embryonic Cartilage and Bone for Gene Expression Analysis

Published on: December 18, 2019

7.5K

科学领域:

  • 发展生物学 发展生物学
  • 进行比较基因组学.
  • 哺乳动物生理学哺乳动物生理学

背景情况:

  • 骨肌对于哺乳动物的功能至关重要,其发育受到复杂的基因调节的控制.
  • 了解骨肌内的多种细胞类型和沟通是至关重要的,但不完整的.
  • 现有的知识缺乏全面的单细胞数据,用于产前至产后的骨肌肉发育.

研究的目的:

  • 创建一个全面的单细胞转录的景观,开发牛骨肌肉.
  • 将牛骨肌肉发育与人类和小鼠模型进行比较.
  • 为了确定哺乳动物骨肌肉进化中的保存和分离特征.

主要方法:

  • 牛骨肌的单细胞RNA测序 (scRNA-seq) 从产前到产后阶段进行.
  • 牛,人类和老鼠数据集之间的比较转录组分析.
  • 基因调节网络和细胞间通信地图的构建.

主要成果:

  • 在牛骨肌肉发育过程中详细的细胞异质性和动态基因表达.
  • 确定控制细胞命运决策的关键调控子.
  • 发现了广泛的细胞间通信网络和基因调节模式.
  • 揭示了在牛,人类和小鼠中保留的发育多能性谱.

结论:

  • 牛骨肌肉发育与人类和小鼠具有保留的多能性特征.
  • 在细胞类型,基因表达和调控元素方面存在显著的特定物种差异.
  • 这项研究提供了有关哺乳动物骨肌肉发育的保存和分化的进化过程的见解.