在压力挑战期间为牛犊养一种基于Bacillus的益生菌:对料摄入,免疫和代谢反应的影响
Shea J Mackey1, Reinaldo F Cooke1, Izadora S De Souza1
1Department of Animal Science, Texas A&M University, College Station, TX 77843.
Journal of animal science
|December 3, 2025
概括
基于细菌的益生菌改善了牛肉的料摄入量,并减少了牛肉的炎症反应,这些牛受到疫苗或脂多糖 (LPS) 的挑战. 这些发现表明,益生菌可以减轻牛群中与压力有关的影响.
科学领域:
- 动物科学动物科学
- 免疫学 免疫学 免疫学
- 微生物学 微生物学
背景情况:
- 牛牛面临的免疫和代谢挑战来自疫苗接种,LPS暴露和运输压力.
- 益生菌,特别是基于Bacillus的菌株,正在被探索,因为它们有可能调节宿主反应.
- 了解益生菌对牲畜应激弹性的影响,对于动物福利和生产力至关重要.
研究的目的:
- 评估一种基于Bacillus的益生菌在减轻牛肉的免疫和代谢应激反应中的有效性.
- 评估益生菌在各种压力条件下对料摄入的影响.
- 为了研究益生菌补充后免疫基因表达的分子水平变化.
主要方法:
- 进行了三项为期35天的实验,对安格斯影响的一年 (n=16) 进行了实验.
- 治疗包括以玉米为基础的缩物,含有或不含Bacillus为基础的益生菌 (3g/人/天).
- 与疫苗接种相关的挑战 (例如. 1),脂聚糖胺 (LPS) 注射 (例如 2),以及24小时运输 (Exp. 3),测量了料摄入量,直肠温度和血液参数.
主要成果:
- 益生菌补充剂缓解了疫苗和LPS挑战后的炎症反应 (降低TNF-α,哈普托格洛宾,LPS结合蛋白).
- 接受益生菌的母牛在LPS挑战后改善了料摄入量,并减少了与炎症和氧化压力相关的基因 (TNFa,TH1,GPx,SOD1mRNA) 的表达.
- 在运输挑战期间没有观察到任何显著的影响,除了葡萄糖和BHB水平的短暂变化.
结论:
- 基于细菌的益生菌可以有效地缓解炎症反应,并改善免疫应激的牛犊的代谢状态.
- 益生菌补充证明了提高压力抵抗力和支持牛的料摄入的潜力.
- 进一步的研究可能会探索不同畜牧生产系统的最佳细菌菌株和剂量.
关键词:
百日 spp 百日是一种免疫力是一种免疫力.这是一种炎症炎症炎症炎症.脂多糖类糖化物 (Lipopolysaccharide) 是一种脂多糖类糖.交通运输运输运输运输运输运输运输运输运输疫苗 疫苗 疫苗 疫苗更多相关视频
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