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Updated: Jan 9, 2026

A Primary Human Trophoblast Model to Study the Effect of Inflammation Associated with Maternal Obesity on Regulation of Autophagy in the Placenta
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A Primary Human Trophoblast Model to Study the Effect of Inflammation Associated with Maternal Obesity on Regulation of Autophagy in the Placenta

Published on: September 27, 2017

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孕产妇肥胖导致肌肉功能障碍通过H19介导的胰岛素类生长因子2信号编程

Sharmeen Islam1, Xinrui Li1, M D Nazmul Hossain1

  • 1Nutrigenomics and Growth Biology Laboratory, Department of Animal Sciences, Washington State University, Pullman, WA.

Diabetes
|December 3, 2025
PubMed
概括

孕产妇肥胖 (MO) 会增加H19的表达,破坏胰岛素样生长因子2 (IGF2) 信号传递,并影响后代的肌肉发育. 这种表观遗传干扰导致长期肌肉功能障碍,突出显示了潜在的治疗标.

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