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相关概念视频

Brain Imaging01:14

Brain Imaging

640
Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans),  magnetic resonance imaging (MRI),  functional magnetic resonance imaging (fMRI), and Transcranial Magnetic...
640

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相关实验视频

Updated: Jan 9, 2026

A Methodological Protocol and Considerations for Transcranial Ultrasonic Stimulation in Exploratory Clinical Human Studies
09:34

A Methodological Protocol and Considerations for Transcranial Ultrasonic Stimulation in Exploratory Clinical Human Studies

Published on: December 12, 2025

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调节人类大脑的功能连接与跨的聚焦超声波刺激.

Amilcar Malave, Emily Valera, Elisa Konofagou

    Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
    |December 3, 2025
    PubMed
    概括

    跨的聚焦超声波刺激 (tFUS) 可以增强子前环皮质 (sgACC) 的功能连接,这是情绪障碍的关键大脑区域. 这种非侵入性技术显示出调节深层大脑活动和治疗应用的潜力.

    科学领域:

    • 神经科学是一个神经科学.
    • 神经调节是一种神经调节.
    • 脑部成像 脑部成像

    背景情况:

    • 超焦点超声刺激 (tFUS) 是一种新的非侵入性神经调节技术.
    • 它的精确机制和对大规模大脑网络的影响尚未完全理解.
    • 前带皮层 (sgACC) 是一个深层大脑区域,与情绪障碍有关.

    研究的目的:

    • 调查tFUS是否可以可靠地调节与sgACC的功能连接 (FC).
    • 评估tFUS对sgACC融入大规模大脑网络的影响.

    主要方法:

    • 功能性磁共振成像 (fMRI) 用于记录血液氧气水平依赖 (BOLD) 活动.
    • 在5分钟的时间里,tFUS针对sgACC.
    • 活动tFUS和假刺激之间进行了比较.

    主要成果:

    • 与假药相比,在tFUS期间和tFUS后立即观察到与sgACC一起的CF的统计学上显著增加.
    • 这种FC的增强是在约80%的sgACC连接中观察到的缓慢增长.
    • 研究结果表明,SgACC可以更好地融入大脑网络.

    结论:

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    Whole-Brain 3D Activation and Functional Connectivity Mapping in Mice using Transcranial Functional Ultrasound Imaging
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    • tFUS可以有效地调节像sgACC这样的大脑深层区域的功能连接.
    • 这些发现支持使用tFUS用于神经调节的可行性.
    • tFUS在精神疾病中具有治疗应用的潜力.