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Updated: Jan 9, 2026

Measuring Mitochondrial Function of Naïve and Effector CD8 T Cells
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氧化酸酸盐通路是T细胞激活和抗瘤免疫的必要条件

Zihong Chen1,2,3, Kellen L Olszewski3, Rolf-Peter Ryseck2,3

  • 1Department of Chemistry, Princeton University, Princeton, NJ 08544.

Proceedings of the National Academy of Sciences of the United States of America
|December 3, 2025
PubMed
概括

葡萄糖-6-酸脱酶 (G6PD) 和6-酸酸脱酶 (PGD) 都对T细胞免疫和免疫治疗反应至关重要. 它们的缺乏会影响T细胞群和存活率,从而损害抗瘤免疫力.

关键词:
它们是NADPH,NADPH.在T细胞激活过程中,抗瘤免疫力T细胞抗瘤免疫力硫化二氧化物的应力压力氧化酸酸盐路径的氧化酸.

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