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Updated: Jan 9, 2026

Adoptive Transfer of IL-33-Stimulated Macrophages into Bleomycin-Induced Mouse Models to Study Their Effect on Idiopathic Pulmonary Fibrosis In Vivo
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Published on: May 5, 2023

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不调节的膜类型2上皮细胞蛋白质稳定促进纤维化巨细胞迁移抑制因子-CD74信号传递

Sang-Hun Kim1, Jessica Nouws1, Jannik Ruwisch2

  • 1Section of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT 06520, USA.

Science translational medicine
|December 3, 2025
PubMed
概括

在肺细胞中破坏无素-蛋白酶体系统通过巨细胞迁移抑制因子 (MIF) 放大纤维化. 准MIF-CD74信号可能治疗异常性肺纤维化 (IPF).

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