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Updated: Jan 9, 2026

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VAPB是STING介导的先天免疫信号传递的负调节者

Wangsheng Ji1, Yin Zhang1, Lianfei Zhang2

  • 1Joint National Laboratory for Antibody Drug Engineering, School of Medicine, Henan University, Kaifeng 475000, China.

Science advances
|December 3, 2025
PubMed
概括

囊泡相关膜蛋白相关蛋白B (VAPB) 负面调节STING通路,这是先天免疫反应的关键部分. 缺少VAPB会增强I型干扰素的产生,并保护人免受HSV-1感染.

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