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Updated: Jan 9, 2026

Development of Inhibitors of Protein-protein Interactions through REPLACE: Application to the Design and Development Non-ATP Competitive CDK Inhibitors
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Development of Inhibitors of Protein-protein Interactions through REPLACE: Application to the Design and Development Non-ATP Competitive CDK Inhibitors

Published on: October 26, 2015

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开发和表征一种穿透膜的GRASP65模拟性,可以抑制戈尔吉解结和细胞循环进展

Romina Ines Cervigni1, Raffaella Bonavita2, Maria Luisa Barretta1

  • 1Institute of Endotypes in Oncology, Metabolism and Immunology "G. Salvatore" (IEOMI), National Research Council (CNR), Via P. Castellino 111, 80131 Naples, Italy.

Methods (San Diego, Calif.)
|December 3, 2025
PubMed
概括

研究人员开发了一种新型,专门抑制戈尔吉丝带解,这是细胞分裂的关键过程. 这种工具有助于研究戈尔吉健康和疾病的复杂动态,包括癌症.

关键词:
细胞周期检查点检查点这是GRASP65的标准.戈尔吉综合体 (Golgi Complex) 是一个高尔基综合体.戈尔吉解锁链接穿透膜的化物.

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Biotinylated Cell-penetrating Peptides to Study Intracellular Protein-protein Interactions10:26

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