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Updated: Jul 24, 2026

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描述TRPV4 ankyrin重复域互动组及其因神经肌肉疾病引起突变的破坏

Alexis K Loder1, Gage P Kosmanopoulos2, William H Aisenberg1

  • 1Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

The Journal of biological chemistry
|December 3, 2025
PubMed
概括

TRPV4的基林重复域 (ARD) 与许多蛋白质相互作用,包括那些参与无处不在和GTPase信号的蛋白质. 致病突变会破坏这些相互作用,影响TRPV4通道功能,并可能导致神经肌肉疾病.

关键词:
环保环境基金 (GEF) 提供在 TRP 频道.的成像成像技术可以帮助我们.神经退行性疾病是一种神经退行性疾病.无处不在的化

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