猪间白蛋白-10的结构性保护和功能性适应:进化见解和病毒仿真

Xiaohui Wei1, Jing Wu1, Suqiu Wang2

  • 1NHC Key Laboratory of Human Disease Comparative Medicine, State Key Laboratory of Respiratory Health and Multimorbidity, National Center of Technology Innovation for Animal Model, Institute of Laboratory Animal Science, Chinese Academy of Medical Sciences and Comparative Medicine Center, Peking Union Medical College, Beijing, China.

概括

猪间蛋白-10 (pIL-10) 与人类IL-10具有结构和功能上的相似性,使猪成为细胞因子研究的有价值模型. 这项研究还揭示了病毒IL-10如何模仿宿主蛋白来逃避免疫.