在2015年至2023年期间,对恶性肺流的存活时间进行了回顾性队列研究
Craig Mounsey1,2, Nikolaos Kanellakis3,4, Dinesh Addala5,3
1Oxford Pleural Unit, Oxford University Hospitals NHS Foundation Trust, Oxford, UK craigmounsey1@gmail.com.
BMJ open respiratory research
|December 3, 2025
概括
尽管在癌症治疗方面取得了进展,但恶性多支流 (MPE) 的存活率并未改善. 这项研究发现2015-2023年间MPE患者的存活时间停滞不前,这表明需要向的多腔空间疗法.
科学领域:
- 在瘤学瘤学.
- 肺部病理学 肺部病理学
- 流行病学 流行病学
背景情况:
- 恶性流 (MPE) 影响~15%的癌症患者.
- 癌症存活率有所改善,但MPE存活率趋势尚不清楚.
研究的目的:
- 调查2015-2023年MPE患者的生存趋势.
- 为了确定最近的管理变化是否影响了MPE存活率.
主要方法:
- 742名MPE患者的医疗记录 (2015-2023) 的回顾性审查.
- 卡普兰-梅尔和考克斯回归生存分析.
- 根据癌症类型,表现状况和治疗方法进行子组分析.
主要成果:
- 在研究期间,MPE患者的存活率没有显著改善.
- 在各种癌症类型和患者子组中,生存率保持停滞.
- 这包括肺癌,中皮瘤,乳腺癌以及接受全身治疗的患者.
结论:
- 尽管癌症总体存活率有所提高,恶性多支流的存活率并没有得到改善.
- MPE可能需要针对腔空间的不同的治疗策略.
- 对MPE的新瘤疗法进行进一步的研究是有必要的.
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