在体外转录酶:研究XNA合成的方法

Lisa Nakayama1, Lijun Zhou1

  • 1Biochemistry, Biophysics, and Chemical Biology Graduate Group, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States; Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States; Penn Institute for RNA Innovation, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.

Methods in enzymology
|December 3, 2025
PubMed
概括

异核酸 (XNA) 为治疗提供了增强的稳定性和结合性. 这项研究详细介绍了一种使用工程聚合酶,SFM 5-7通过体外转录合成XNAs的方法.

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