在亚洲的年轻成年人中,中风的负担及其亚型,1990-2021年:风险因素和未来的预测
Wenbo Li1,2, Qirui Guo3, Cong Gao1,2
1Department of Neurology, Beijing Tiantan Hospital Affiliated to Capital Medical University, Beijing, China.
Stroke and vascular neurology
|December 3, 2025
概括
从1990年到2021年,年轻亚洲成年人 (15-49岁) 的中风负担显著增加. 尽管死亡率下降,但患病率和发病率上升需要针对这一人口群进行有针对性的干预.
科学领域:
- 流行病学 流行病学
- 公共卫生 公共卫生
- 神经学 神经学
背景情况:
- 脑卒中是一个重大的全球健康挑战,人们越来越担心年轻成年人 (15-49岁) 的负担会增加.
- 关于亚洲年轻人的中风负担及其亚型的综合数据仍然有限,阻碍了有针对性的公共卫生战略.
- 了解趋势和风险因素对于亚洲有效的政策制定和资源配置至关重要.
研究的目的:
- 从1990年到2021年,评估亚洲年轻成年人 (15-49岁) 中中风及其亚型的负担.
- 分析中风发病率,发病率,死亡率和残疾调整寿命年 (DALYs) 的趋势.
- 确定主要风险因素,并预测该地区未来的中风趋势.
主要方法:
- 利用了2021年全球疾病,伤害和风险因素负担研究 (GBD) 的数据,用于1990-2021年期间.
- 估计的绝对数量和中风指标 (流行率,发病率,死亡率,DALYs,YLLs,YLDs) 的率,分年,年龄和性别分层.
- 分析了主要的风险因素 (例如,高静脉压,吸烟,空气污染) 并预测到2050年的未来趋势.
主要成果:
- 2021年,中风在亚洲的年轻成年人中占到了1470万个DALY和114万个新病例.
- 从1990年到2021年,绝对中风数量显著增加 (例如,43.56%的患病率,44.82%的发病率),而年龄标准化的死亡率和DALYs下降.
- 缺血性中风 (IS) 显示出比脑内出血 (ICH) 和脑下出血 (SAH) 更明显的增长;负担随着年龄的增长而增加,在男性中更高,特别是在45-49岁的年龄组.
结论:
- 在亚洲的年轻成年人中,中风及其亚型的整体负担从1990年到2021年大幅增加.
- 跨年龄组和性别存在显著差异,45-49岁的男性承受着最高的负担.
- 预计患病率和发病率的增加,加上人口变化,需要针对年轻人的专注公共卫生政策和干预措施.
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