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Updated: Jan 9, 2026

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染色体不稳定的表观遗传驱动因素

Ilio Vitale1, Matteo Cereda2, Lorenzo Galluzzi3

  • 1IIGM, Italian Institute for Genomic Medicine, c/o IRCSS Candiolo, Torino, Italy; Candiolo Cancer Institute, FPO-IRCCS, Candiolo, Italy.

Trends in cancer
|December 3, 2025
PubMed
概括

像DNA甲基化失衡这样的表观遗传缺陷积极推动染色体不稳定性 (CIN),这是癌症发展和治疗耐药性的关键因素. 这些表观遗传变化破坏细胞分裂,导致基因组不稳定,并助长癌症.

关键词:
细胞周期检查点的检查点染色体错误分离的错误分离是什么经过翻译的表述性表述性.内异质性的异质性微核是微核中的一个.线粒体灾难的灾难

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