评估墨西哥制社区的环境污染物暴露和心血管风险
Francisco Javier Pérez-Vázquez1,2, Axel Reyes-Zavala1, Laura Sherell Marín-Jáuregui3
1Coordinación para la Innovación y Aplicación de la Ciencia y la Tecnología (CIACYT), Universidad Autónoma de San Luis Potosí, Sierra Leona 550, Lomas Segunda Sección, 78210, San Luis Potosí, México.
Environmental geochemistry and health
|December 3, 2025
概括
墨西哥的工面临着因职业接触重金属如和以及多环芳 (PAHs) 的高心血管风险. 这种暴露与动原体指数的升高有关,表明心脏病风险增加.
科学领域:
- 环境健康 环境健康
- 职业医学 职业医学 职业医学
- 心血管流行病学心血管流行病学
背景情况:
- 心血管疾病 (CVD) 是全球主要的死亡原因.
- 职业接触环境污染物,包括重金属 (,) 和多环芳 (PAHs),可能会增加心血管疾病的风险.
- 制是一种非正式的职业,有可能长期暴露于这些污染物中.
研究的目的:
- 评估墨西哥巴希奥地区的制者对重金属和PAHs的职业暴露.
- 评估动脉动脉指数作为该人口心血管风险指标.
- 调查污染物暴露与心血管风险标志物之间的关联.
主要方法:
- 一项涉及圣路易斯波托西 (SLP),瓜纳胡阿托 (GTO) 和奎雷塔罗 (QRO) 的113名成年男性匠的横截面研究.
- 对尿液和血液样本进行重金属 (,) 和PAHs的分析.
- 计算脂质资料以确定卡斯特利风险指数 (CRI-I,CRI-II) 和血无氧原体指数 (AIP).
主要成果:
- 瓜纳胡亚托 (GTO) 的尿和PAH暴露率最高,而圣路易斯波托西 (SLP) 的血含量最高.
- 观察到高的动脉动脉指数 (CRI-I,CRI-II,AIP),特别是在GTO.
- 在和暴露和较高的CRI-II值之间发现了显著的关联,表明脂质代谢中断.
结论:
- 巴吉奥地区的制人群表现出职业接触环境污染物的情况.
- 长期暴露于和与心血管风险增加有关,由升高的动脉质指数表明.
- 这些发现强调了需要采取干预措施,以减轻职业危险,并减少脆弱的工人群体中心血管疾病风险.
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