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转录共抑制改变了耐药性的演变,并增强了Mycobacterium 结核病从颗粒瘤的清除

Barbara Bosch1, Vanisha Munsamy-Govender2, Jansy Sarathy3,4

  • 1Laboratory of Molecular Pathogenesis, The Rockefeller University, New York, NY, USA. bbosch@rockefeller.edu.

Nature microbiology
|December 3, 2025
PubMed
概括

一种名为AAP-SO2的新药向了导致结核病的细菌Mycobacterium tuberculosis (Mtb) 的转录周期. 这种方法可以对抗利芬素耐药性,并有效清除持久的Mtb种群.

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