来自亲炎性M1巨细胞的细胞外囊泡在黑色素瘤细胞中诱导炎症和侵入性表型

Kaisa Mäki-Mantila1, Einari A Niskanen2, Kirsi Kainulainen2

  • 1Institute of Biomedicine, School of Medicine, University of Eastern Finland, Kuopio, Finland. kaisa.maki-mantila@uef.fi.

概括

支持炎症的M1巨细胞外囊泡 (EVs) 重新编程黑色素瘤细胞,通过NF-κB信号和瘤相关炎症增加入侵. 这突显了黑色素瘤进展中的EV介导通信.

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