多种定数感应系统调节深海冷的微生物通信和生物地化学过程
Jiaxue Peng1,2, Xinyue Liu1, Jieni Wang1
1Key Laboratory of Marine Genetic Resources, Third Institute of Oceanography, Ministry of Natural Resources, Xiamen, 361005, China.
Microbiome
|December 4, 2025
概括
微生物通过定数感应 (QS) 进行通信,在深海冷中很普遍,调节关键的代谢群体并影响生物地质化学循环. 这项研究揭示了QS网络的复杂性及其在这些独特环境中的生态作用.
科学领域:
- 微生物学 微生物学
- 深海生态 深海生态
- 生物地质化学生物地质化学
背景情况:
- 定数感应 (QS) 是一种关键的微生物通信机制,用于协调行为和适应.
- 它在由多样化的微生物群落特征的深海冷透生态系统中的作用尚不清楚.
- 这项研究调查了QS在冷的发生和生态意义.
研究的目的:
- 为了阐明在深海冷透环境中,定数感应基因的存在和分布.
- 了解量子感应在微生物相互作用和生物地化学循环中的潜在生态作用.
- 为了确定关键的定数感应系统和蛋白质参与微生物调节在冷透.
主要方法:
- 来自17个全球冷点的170个元基因组和33个元转录组的分析.
- 识别和编目定决数感应基因和相关蛋白质.
- 遗传学分析,蛋白质域识别,异质表达和代谢分析.
主要成果:
- 在34个类型和6个系统中确定了299,355个定数感知基因,分布受环境因素的影响.
- 在3576个基因组中发现了32500个QS基因,表明复杂的物种内部和物种间的通信网络.
- 发现QS广泛调节关键的微生物群 (例如,减少硫酸盐的细菌,古生物) 参与生物地化学循环.
结论:
- 质量检测在微生物相互作用,适应和生物地化学循环中扮演着复杂而重要的角色.
- 这些发现有助于我们更好地理解深层生物圈中的微生物交流.
- 暗示冷沉积物中存在质量检测抑制剂.
相关概念视频
01:28Gene Regulation in Microbial Communities: Quorum Sensing
473
Quorum sensing is a mechanism of bacterial communication that enables coordinated gene expression in response to changes in population density. This facilitates collective behaviors that enhance survival, resource acquisition, and ecological adaptation. This process relies on small signaling molecules called autoinducers that accumulate as bacterial populations grow. When a critical threshold concentration of autoinducers is reached, bacterial cells collectively modify gene expression,...
473
01:30Bacterial Signaling
40.0K
Bacterial signaling can occur within bacteria (intracellular) or between bacteria (intercellular). At times, a group of bacteria behaves like a community. To achieve this, they engage in quorum sensing, the perception of higher cell density that causes changes in gene expression. Quorum sensing involves both extracellular and intracellular signaling. The signaling cascade starts with a molecule called an autoinducer (AI). Individual bacteria produce AIs that move out of the bacterial cell...
40.0K
01:28Global Regulatory Systems
564
Global regulatory systems in bacteria enable rapid and coordinated responses to environmental changes by integrating sensory inputs with gene expression, ensuring efficient adaptation to fluctuating conditions. Key global regulatory mechanisms include regulons, two-component systems, sigma factors, and secondary messengers.Regulons and Global RegulatorsA regulon is a collection of genes and operons controlled by a common global regulator. These regulators enable bacteria to prioritize resource...
564
01:28Carbon-dioxide Fixation
597
Carbon dioxide fixation in prokaryotes enables the assimilation of inorganic carbon into organic molecules, supporting biosynthetic pathways, sustaining ecosystems, and contributing to the global carbon cycle. It also has industrial applications in carbon capture and bioproduct synthesis. Autotrophic organisms rely on this process to utilize CO₂ as a carbon source in diverse environments.The Calvin CycleThe Calvin cycle is the most widespread carbon fixation mechanism, primarily used by...
597
01:30Other Stress Responses in Bacteria
314
Bacteria have global regulatory systems that control several types of stress mechanisms. These include Pho regulon and the heat shock response, which are essential systems for environmental adaptation, such as nutrient limitation and proteotoxic stress. The Pho regulon and the heat shock response exemplify bacterial resilience, enabling rapid adaptation to fluctuating environmental conditions.Pho RegulonBacteria require phosphorus for essential cellular processes, including nucleic acid...
314
01:23Stringent Response in E. coli
267
Bacterial growth is closely tied to nutrient availability, with cells proliferating exponentially under favorable conditions and entering a stationary phase when resources become scarce. This transition is mediated by a regulatory mechanism known as the stringent response, which allows bacteria to adapt to nutrient deprivation by modulating gene expression and metabolic activity.During nutrient scarcity, intracellular amino acid levels decline. It results in the accumulation of uncharged tRNAs...
267